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pentobarbital will minimize the extent or result of netupitant/palonosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Netupitant is mainly metabolized by CYP3A4; stay clear of use in individuals who will be chronically applying a robust CYP3A4 inducerpentobarbital will reduce the level or resu